BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4

Hepatocellular carcinoma (HCC) is one of the most prevalent and poorly responsive cancers worldwide. Bromodomain and extraterminal (BET) inhibitors, such as JQ1 and OTX-015, inhibit BET protein binding to acetylated residues in histones. However, the physiological mechanisms and regulatory processes...

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Detalles Bibliográficos
Autores principales: Choi, Hae In, An, Ga Yeong, Baek, Mina, Yoo, Eunyoung, Chai, Jin Choul, Lee, Young Seek, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175750/
https://www.ncbi.nlm.nih.gov/pubmed/34083693
http://dx.doi.org/10.1038/s41598-021-91284-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175750/
https://www.ncbi.nlm.nih.gov/pubmed/34083693
http://dx.doi.org/10.1038/s41598-021-91284-2

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