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Complete Correction of Brain and Spinal Cord Pathology in Metachromatic Leukodystrophy Mice
Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder characterized by accumulation of sulfatides in both glial cells and neurons. MLD results from an inherited deficiency of arylsulfatase A (ARSA) and myelin degeneration in the central and peripheral nervous systems. Currently, no effe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175802/ https://www.ncbi.nlm.nih.gov/pubmed/34093126 http://dx.doi.org/10.3389/fnmol.2021.677895 |