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LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripotency in porcine induced pluripotent stem cells

LIN28A, an RNA-binding protein, plays an important role in porcine induced pluripotent stem cells (piPSCs). However, the molecular mechanism underlying the function of LIN28A in the maintenance of pluripotency in piPSCs remains unclear. Here, we explored the function of LIN28A in piPSCs based on its...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-Long, Zhu, Zhen-Shuo, Xiao, Xia, Zhou, Zhe, Yu, Shuai, Shen, Qiao-Yan, Zhang, Ju-Qing, Yue, Wei, Zhang, Rui, He, Xin, Peng, Sha, Zhang, Shi-Qiang, Li, Na, Liao, Ming-Zhi, Hua, Jin-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175949/
https://www.ncbi.nlm.nih.gov/pubmed/33998185
http://dx.doi.org/10.24272/j.issn.2095-8137.2020.375