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HOXA13, Negatively Regulated by miR-139-5p, Decreases the Sensitivity of Gastric Cancer to 5-Fluorouracil Possibly by Targeting ABCC4

PURPOSE: Chemoresistance remains a major challenge in the therapy of gastric cancer (GC). The homeobox (HOX) gene family has gained attention in carcinogenesis and chemoresistance. Here, this study aimed to explore the mechanism of HOXA13 in GC chemoresistance. METHODS: Quantitative real-time PCR (q...

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Detalles Bibliográficos
Autores principales: Chen, Zhengqian, Qin, Zhiwei, Li, Lei, Wo, Qi, Chen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175971/
https://www.ncbi.nlm.nih.gov/pubmed/34094932
http://dx.doi.org/10.3389/fonc.2021.645979