γ-secretase inhibitors, DAPT and RO4929097, promote the migration of Human Glioma Cells via Smad5-downregulated E-cadherin Expression

Malignant gliomas are a type of central nervous system cancer with extremely high mortality rates in humans. γ-secretase has been becoming a potential target for cancer therapy, including glioma, because of the involvement of its enzymatic activity in regulating the proliferation and metastasis of c...

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Detalles Bibliográficos
Autores principales: Chang, Shun-Fu, Yang, Wei-Hsun, Cheng, Chun-Yu, Luo, Sheng-Jie, Wang, Ting-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176174/
https://www.ncbi.nlm.nih.gov/pubmed/34104086
http://dx.doi.org/10.7150/ijms.50484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176174/
https://www.ncbi.nlm.nih.gov/pubmed/34104086
http://dx.doi.org/10.7150/ijms.50484

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