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Liver Transcriptome Dynamics During Hibernation Are Shaped by a Shifting Balance Between Transcription and RNA Stability

Hibernators dramatically lower metabolism to save energy while fasting for months. Prolonged fasting challenges metabolic homeostasis, yet small-bodied hibernators emerge each spring ready to resume all aspects of active life, including immediate reproduction. The liver is the body’s metabolic hub,...

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Detalles Bibliográficos
Autores principales: Gillen, Austin E., Fu, Rui, Riemondy, Kent A., Jager, Jennifer, Fang, Bin, Lazar, Mitchell A., Martin, Sandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176218/
https://www.ncbi.nlm.nih.gov/pubmed/34093224
http://dx.doi.org/10.3389/fphys.2021.662132