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The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma
Repetitive exposure of Rag1(−/−) mice to the Alternaria allergen extract generated a form of memory that elicited an asthma-like response upon a subthreshold recall challenge 3–15 wk later. This memory was associated with lung ICOS(+)ST2(+) ILC2s. Genetic, pharmacologic, and antibody-mediated inhibi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176441/ https://www.ncbi.nlm.nih.gov/pubmed/34076685 http://dx.doi.org/10.1084/jem.20201354 |