Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models

[Image: see text] Aggregated tau protein is a core pathology present in several neurodegenerative diseases. Therefore, the development and application of positron emission tomography (PET) imaging radiotracers that selectively bind to aggregated tau in fibril form is of importance in furthering the...

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Detalles Bibliográficos
Autores principales: McMurray, Lindsay, Macdonald, Jennifer A., Ramakrishnan, Nisha Kuzhuppilly, Zhao, Yanyan, Williamson, David W., Tietz, Ole, Zhou, Xiaoyun, Kealey, Steven, Fagan, Steven G., Smolek, Tomáš, Cubinkova, Veronika, Žilka, Norbert, Spillantini, Maria Grazia, Tolkovsky, Aviva M., Goedert, Michel, Aigbirhio, Franklin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176454/
https://www.ncbi.nlm.nih.gov/pubmed/33689290
http://dx.doi.org/10.1021/acschemneuro.0c00790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176454/
https://www.ncbi.nlm.nih.gov/pubmed/33689290
http://dx.doi.org/10.1021/acschemneuro.0c00790

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