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Common Reference-Based Tandem Mass Tag Multiplexing for the Relative Quantification of Peptides: Design and Application to Degradome Analysis of Diphtheria Toxoid

[Image: see text] Currently, animal tests are being used to confirm the potency and lack of toxicity of toxoid vaccines. In a consistency approach, animal tests could be replaced if production consistency (compared to known good products) can be proven in a panel of in vitro assays. By mimicking the...

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Detalles Bibliográficos
Autores principales: Michiels, Thomas J. M., van Veen, Madelief A., Meiring, Hugo D., Jiskoot, Wim, Kersten, Gideon F. A., Metz, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176455/
https://www.ncbi.nlm.nih.gov/pubmed/33983728
http://dx.doi.org/10.1021/jasms.1c00070