Identification of Docetaxel as a Potential Drug to Promote HDL Biogenesis

Objective: Our recent studies showed that desmocollin 1 (DSC1) binds to apoA-I in order to inhibit apoA-I-mediated high density lipoprotein (HDL) biogenesis in atherosclerotic plaques. To promote HDL biogenesis in the plaque, here we search for small molecules that block apoA-I-DSC1 interactions. Ap...

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Detalles Bibliográficos
Autores principales: Choi, Hong Y., Ruel, Isabelle, Genest, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176524/
https://www.ncbi.nlm.nih.gov/pubmed/34093205
http://dx.doi.org/10.3389/fphar.2021.679456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176524/
https://www.ncbi.nlm.nih.gov/pubmed/34093205
http://dx.doi.org/10.3389/fphar.2021.679456

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