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A rat model for retinitis pigmentosa with rapid retinal degeneration enables drug evaluation in vivo

BACKGROUND: Although retinitis pigmentosa (RP) is most frequently studied in mouse models, rats, rabbits, and pigs are also used as animal models of RP. However, no studies have reported postnatal photoreceptor cell loss before complete development in these models. Here, we generated a transgenic ra...

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Detalles Bibliográficos
Autores principales: Inoue, Chisato, Takeuchi, Tamaki, Shiota, Akira, Kondo, Mineo, Nshizawa, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176615/
https://www.ncbi.nlm.nih.gov/pubmed/34088267
http://dx.doi.org/10.1186/s12575-021-00150-y