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Druggability of cavity pockets within SARS-CoV-2 spike glycoprotein and pharmacophore-based drug discovery

Aim: Virus spike glycoprotein of SARS-CoV-2 is a good target for drug discovery. Objective: To examine the potential for druggability of spike protein for pharmacophore-based drug discovery and to investigate the binding affinity of natural products with SARS-CoV-2 spike protein. Methods: Druggable...

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Detalles Bibliográficos
Autores principales: Mohebbi, Alireza, Askari, Fatemeh Sana, Sammak, Ali Salehnia, Ebrahimi, Mohsen, Najafimemar, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176656/
https://www.ncbi.nlm.nih.gov/pubmed/34099962
http://dx.doi.org/10.2217/fvl-2020-0394