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Fusion of single-cell transcriptome and DNA-binding data, for genomic network inference in cortical development

BACKGROUND: Network models are well-established as very useful computational-statistical tools in cell biology. However, a genomic network model based only on gene expression data can, by definition, only infer gene co-expression networks. Hence, in order to infer gene regulatory patterns, it is nec...

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Detalles Bibliográficos
Autor principal: Bartlett, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176738/
https://www.ncbi.nlm.nih.gov/pubmed/34088262
http://dx.doi.org/10.1186/s12859-021-04201-9