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Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates

BACKGROUND: The development of regenerative therapy for human spinal cord injury (SCI) is dramatically restricted by two main challenges: the need for a safe source of functionally active and reproducible neural stem cells and the need of adequate animal models for preclinical testing. Direct reprog...

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Detalles Bibliográficos
Autores principales: Baklaushev, Vladimir P, Durov, Oleg V, Kalsin, Vladimir A, Gulaev, Eugene V, Kim, Sergey V, Gubskiy, Ilya L, Revkova, Veronika A, Samoilova, Ekaterina M, Melnikov, Pavel A, Karal-Ogly, Dzhina D, Orlov, Sergey V, Troitskiy, Alexander V, Chekhonin, Vladimir P, Averyanov, Alexander V, Ahlfors, Jan-Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176843/
https://www.ncbi.nlm.nih.gov/pubmed/34136075
http://dx.doi.org/10.4252/wjsc.v13.i5.452