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A Dynamic Transcription Factor Signature Along the Colorectal Adenoma-Carcinoma Sequence in Patients With Co-Occurrent Adenoma and Carcinoma

BACKGROUND: Colorectal carcinoma (CRC) often arises from benign adenoma after a stepwise accumulation of genetic alterations. Here, we profiled the dynamic landscapes of transcription factors (TFs) in the mucosa-adenoma-carcinoma progression sequence. METHODS: The transcriptome data of co-occurrent...

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Detalles Bibliográficos
Autores principales: Pan, Zongfu, He, Ying, Zhu, Wenjuan, Xu, Tong, Hu, Xiaoping, Huang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176860/
https://www.ncbi.nlm.nih.gov/pubmed/34094897
http://dx.doi.org/10.3389/fonc.2021.597447