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Notch3-Dependent Effects on Adult Neurogenesis and Hippocampus-Dependent Learning in a Modified Transgenic Model of CADASIL

We and others have reported that Notch3 is a regulator of adult hippocampal neurogenesis. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), the most common genetic form of vascular dementia, is caused by mutations in Notch3. The present study inten...

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Detalles Bibliográficos
Autores principales: Ehret, Fanny, Moreno Traspas, Ricardo, Neumuth, Marie-Theres, Hamann, Bianca, Lasse, Daniela, Kempermann, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177050/
https://www.ncbi.nlm.nih.gov/pubmed/34093162
http://dx.doi.org/10.3389/fnagi.2021.617733