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Bone marrow derived mast cells injected into the osteoarthritic knee joints of mice induced by sodium monoiodoacetate enhanced spontaneous pain through activation of PAR2 and action of extracellular ATP

Conditions that resemble osteoarthritis (OA) were produced by injection of sodium monoiodoacetate (MIA) into the knee joints of mice. Bone marrow derived mast cells (BMMCs) injected into the OA knee joints enhanced spontaneous pain. Since no spontaneous pain was observed when BMMCs were injected int...

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Detalles Bibliográficos
Autores principales: Habuchi, Hiroko, Izumi, Masashi, Dan, Junpei, Ushida, Takahiro, Ikeuchi, Masahiko, Takeuchi, Kosei, Habuchi, Osami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177436/
https://www.ncbi.nlm.nih.gov/pubmed/34086763
http://dx.doi.org/10.1371/journal.pone.0252590