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Bone marrow derived mast cells injected into the osteoarthritic knee joints of mice induced by sodium monoiodoacetate enhanced spontaneous pain through activation of PAR2 and action of extracellular ATP
Conditions that resemble osteoarthritis (OA) were produced by injection of sodium monoiodoacetate (MIA) into the knee joints of mice. Bone marrow derived mast cells (BMMCs) injected into the OA knee joints enhanced spontaneous pain. Since no spontaneous pain was observed when BMMCs were injected int...
Autores principales: | Habuchi, Hiroko, Izumi, Masashi, Dan, Junpei, Ushida, Takahiro, Ikeuchi, Masahiko, Takeuchi, Kosei, Habuchi, Osami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177436/ https://www.ncbi.nlm.nih.gov/pubmed/34086763 http://dx.doi.org/10.1371/journal.pone.0252590 |
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