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Calculation of the force field required for nucleus deformation during cell migration through constrictions

During cell migration in confinement, the nucleus has to deform for a cell to pass through small constrictions. Such nuclear deformations require significant forces. A direct experimental measure of the deformation force field is extremely challenging. However, experimental images of nuclear shape a...

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Detalles Bibliográficos
Autores principales: Estabrook, Ian D., Thiam, Hawa Racine, Piel, Matthieu, Hawkins, Rhoda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177636/
https://www.ncbi.nlm.nih.gov/pubmed/34029312
http://dx.doi.org/10.1371/journal.pcbi.1008592