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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Hepatocellular carcinoma (HCC) is driven by repeated rounds of inflammation, leading to fibrosis, cirrhosis, and, ultimately, cancer. A critical step in HCC formation is the transition from fibrosis to cirrhosis, which is associated with a change in the liver parenchyma called ductular reaction. Her...

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Detalles Bibliográficos
Autores principales: Barthet, Valentin J. A., Brucoli, Martina, Ladds, Marcus J. G. W., Nössing, Christoph, Kiourtis, Christos, Baudot, Alice D., O’Prey, James, Zunino, Barbara, Müller, Miryam, May, Stephanie, Nixon, Colin, Long, Jaclyn S., Bird, Thomas G., Ryan, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177709/
https://www.ncbi.nlm.nih.gov/pubmed/34088666
http://dx.doi.org/10.1126/sciadv.abf9141