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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
Hepatocellular carcinoma (HCC) is driven by repeated rounds of inflammation, leading to fibrosis, cirrhosis, and, ultimately, cancer. A critical step in HCC formation is the transition from fibrosis to cirrhosis, which is associated with a change in the liver parenchyma called ductular reaction. Her...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177709/ https://www.ncbi.nlm.nih.gov/pubmed/34088666 http://dx.doi.org/10.1126/sciadv.abf9141 |