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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
Hepatocellular carcinoma (HCC) is driven by repeated rounds of inflammation, leading to fibrosis, cirrhosis, and, ultimately, cancer. A critical step in HCC formation is the transition from fibrosis to cirrhosis, which is associated with a change in the liver parenchyma called ductular reaction. Her...
Autores principales: | Barthet, Valentin J. A., Brucoli, Martina, Ladds, Marcus J. G. W., Nössing, Christoph, Kiourtis, Christos, Baudot, Alice D., O’Prey, James, Zunino, Barbara, Müller, Miryam, May, Stephanie, Nixon, Colin, Long, Jaclyn S., Bird, Thomas G., Ryan, Kevin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177709/ https://www.ncbi.nlm.nih.gov/pubmed/34088666 http://dx.doi.org/10.1126/sciadv.abf9141 |
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