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Conversion of mouse embryonic fibroblasts into neural crest cells and functional corneal endothelia by defined small molecules
Reprogramming of somatic cells into desired functional cell types by small molecules has vast potential for developing cell replacement therapy. Here, we developed a stepwise strategy to generate chemically induced neural crest cells (ciNCCs) and chemically induced corneal endothelial cells (ciCECs)...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177713/ https://www.ncbi.nlm.nih.gov/pubmed/34088673 http://dx.doi.org/10.1126/sciadv.abg5749 |