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Conversion of mouse embryonic fibroblasts into neural crest cells and functional corneal endothelia by defined small molecules

Reprogramming of somatic cells into desired functional cell types by small molecules has vast potential for developing cell replacement therapy. Here, we developed a stepwise strategy to generate chemically induced neural crest cells (ciNCCs) and chemically induced corneal endothelial cells (ciCECs)...

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Detalles Bibliográficos
Autores principales: Pan, Shao-Hui, Zhao, Ning, Feng, Xiang, Jie, Ying, Jin, Zi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177713/
https://www.ncbi.nlm.nih.gov/pubmed/34088673
http://dx.doi.org/10.1126/sciadv.abg5749