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PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma

Metastasis is a major obstacle to better prognosis in patients with hepatocellular carcinoma (HCC). Mesenchymal‐epithelial transition (MET) is the driving force for metastatic colonization in which E‐cadherin re‐expression is a critical procedure. It has been reported that the loss of paired‐related...

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Detalles Bibliográficos
Autores principales: Chen, Weibo, Wu, Junyi, Shi, Weiwei, Zhang, Guang, Chen, Xuemin, Ji, Anlai, Wang, Zhongxia, Wu, Junhua, Jiang, Chunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177778/
https://www.ncbi.nlm.nih.gov/pubmed/33587761
http://dx.doi.org/10.1111/cas.14853