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Transcriptional dysregulation by aberrant enhancer activation and rewiring in cancer

Cell identity is controlled by regulatory elements, such as promoters, enhancers, and insulators, within the genome. These regulatory elements interact in the nucleus and form tissue‐specific chromatin structures. Dysregulation of these elements and their interactions can lead to loss of cell identi...

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Detalles Bibliográficos
Autores principales: Okabe, Atsushi, Kaneda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177786/
https://www.ncbi.nlm.nih.gov/pubmed/33728716
http://dx.doi.org/10.1111/cas.14884