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Transcriptional dysregulation by aberrant enhancer activation and rewiring in cancer
Cell identity is controlled by regulatory elements, such as promoters, enhancers, and insulators, within the genome. These regulatory elements interact in the nucleus and form tissue‐specific chromatin structures. Dysregulation of these elements and their interactions can lead to loss of cell identi...
Autores principales: | Okabe, Atsushi, Kaneda, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177786/ https://www.ncbi.nlm.nih.gov/pubmed/33728716 http://dx.doi.org/10.1111/cas.14884 |
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