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OTUB1 facilitates bladder cancer progression by stabilizing ATF6 in response to endoplasmic reticulum stress
The unfolded protein response (UPR) plays an important role in carcinogenesis, but the functional role and mechanism of UPR‐associated bladder carcinogenesis remain to be characterized. Upon UPR activation, ATF6α is activated to upregulate the transcription of UPR target genes. Although the mechanis...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177800/ https://www.ncbi.nlm.nih.gov/pubmed/33686769 http://dx.doi.org/10.1111/cas.14876 |