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OTUB1 facilitates bladder cancer progression by stabilizing ATF6 in response to endoplasmic reticulum stress

The unfolded protein response (UPR) plays an important role in carcinogenesis, but the functional role and mechanism of UPR‐associated bladder carcinogenesis remain to be characterized. Upon UPR activation, ATF6α is activated to upregulate the transcription of UPR target genes. Although the mechanis...

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Detalles Bibliográficos
Autores principales: Zhang, Hui‐Hui, Li, Chao, Ren, Jian‐Wei, Liu, Lian, Du, Xue‐Hua, Gao, Jie, Liu, Tao, Li, Shang‐Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177800/
https://www.ncbi.nlm.nih.gov/pubmed/33686769
http://dx.doi.org/10.1111/cas.14876