Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau

Abnormal protein accumulation and mislocalization is a general hallmark of Alzheimer disease. Recent data suggest nucleocytoplasmic transport may be compromised by tau in Alzheimer disease. In this context, we have examined the RNA polymerase II subunit RPB1, which is the catalytic subunit that play...

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Detalles Bibliográficos
Autores principales: Dickson, John R, Yoon, Hyejin, Frosch, Matthew P, Hyman, Bradley T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177848/
https://www.ncbi.nlm.nih.gov/pubmed/33990839
http://dx.doi.org/10.1093/jnen/nlab040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177848/
https://www.ncbi.nlm.nih.gov/pubmed/33990839
http://dx.doi.org/10.1093/jnen/nlab040

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