Short and long sleeping mutants reveal links between sleep and macroautophagy

Sleep is a conserved and essential behavior, but its mechanistic and functional underpinnings remain poorly defined. Through unbiased genetic screening in Drosophila, we discovered a novel short-sleep mutant we named argus. Positional cloning and subsequent complementation, CRISPR/Cas9 knock-out, an...

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Detalles Bibliográficos
Autores principales: Bedont, Joseph L, Toda, Hirofumi, Shi, Mi, Park, Christine H, Quake, Christine, Stein, Carly, Kolesnik, Anna, Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177895/
https://www.ncbi.nlm.nih.gov/pubmed/34085929
http://dx.doi.org/10.7554/eLife.64140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177895/
https://www.ncbi.nlm.nih.gov/pubmed/34085929
http://dx.doi.org/10.7554/eLife.64140

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