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Short and long sleeping mutants reveal links between sleep and macroautophagy
Sleep is a conserved and essential behavior, but its mechanistic and functional underpinnings remain poorly defined. Through unbiased genetic screening in Drosophila, we discovered a novel short-sleep mutant we named argus. Positional cloning and subsequent complementation, CRISPR/Cas9 knock-out, an...
Autores principales: | Bedont, Joseph L, Toda, Hirofumi, Shi, Mi, Park, Christine H, Quake, Christine, Stein, Carly, Kolesnik, Anna, Sehgal, Amita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177895/ https://www.ncbi.nlm.nih.gov/pubmed/34085929 http://dx.doi.org/10.7554/eLife.64140 |
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