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A pro-inflammatory mediator USP11 enhances the stability of p53 and inhibits KLF2 in intracerebral hemorrhage

Microglial cell activation and neuroinflammation after intracerebral hemorrhage (ICH) lead to secondary brain damage. Ubiquitin-specific protease 11 (USP11) has been correlated with ICH-induced neuron apoptosis. This study aims to explore the molecular mechanism of USP11 regulating neuroinflammation...

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Detalles Bibliográficos
Autores principales: Zhang, Xiuqing, Liu, Tiejun, Xu, Shijun, Gao, Peng, Dong, Wei, Liu, Weiran, Gao, Ming, Song, Lihua, Cui, Lusha, Dong, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178085/
https://www.ncbi.nlm.nih.gov/pubmed/34141823
http://dx.doi.org/10.1016/j.omtm.2021.01.015