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Does administration of hydroxychloroquine/amiodarone accelerate accumulation of globotriaosylceramide and globotriaosylsphingosine in Fabry mice?

Drug-induced lysosomal storage disease (DILSD) caused by cationic amphiphilic drugs (CADs), which exhibits toxic manifestations and pathological findings mimicking Fabry disease (α-galactosidase A deficiency), has attracted the interests of clinicians and pathologists. Although the affected region i...

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Detalles Bibliográficos
Autores principales: Tsukimura, Takahiro, Shiga, Tomoko, Saito, Koki, Ogawa, Yasuhiro, Sakuraba, Hitoshi, Togawa, Tadayasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178118/
https://www.ncbi.nlm.nih.gov/pubmed/34136356
http://dx.doi.org/10.1016/j.ymgmr.2021.100773