Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe(–/–) mice

OBJECTIVE: Interferon regulatory factor (IRF) 5 is a transcription factor known for promoting M1 type macrophage polarization in vitro. Given the central role of inflammatory macrophages in promoting atherosclerotic plaque progression, we hypothesize that myeloid cell-specific deletion of IRF5 is pr...

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Detalles Bibliográficos
Autores principales: Leipner, Julia, Dederichs, Tsai-Sang, von Ehr, Alexander, Rauterberg, Simon, Ehlert, Carolin, Merz, Julian, Dufner, Bianca, Hoppe, Natalie, Krebs, Katja, Heidt, Timo, von zur Muehlen, Constantin, Stachon, Peter, Ley, Klaus, Wolf, Dennis, Zirlik, Andreas, Bode, Christoph, Hilgendorf, Ingo, Härdtner, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178123/
https://www.ncbi.nlm.nih.gov/pubmed/33991749
http://dx.doi.org/10.1016/j.molmet.2021.101250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178123/
https://www.ncbi.nlm.nih.gov/pubmed/33991749
http://dx.doi.org/10.1016/j.molmet.2021.101250

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