The acyl chains of phosphoinositide PIP3 alter the structure and function of nuclear receptor steroidogenic factor-1

Nuclear receptors are transcription factors that bind lipids, an event that induces a structural conformation of the receptor that favors interaction with transcriptional coactivators. The nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) binds the signaling phosphoinositides PI(4,5)P2 (PIP2) an...

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Detalles Bibliográficos
Autores principales: Bryant, Jamal M., Malabanan, M. Merced, Vanderloop, Boden H., Nichols, Charles M., Haratipour, Zeinab, Poon, Katrina T., Sherrod, Stacy D., McLean, John A., Blind, Raymond D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178125/
https://www.ncbi.nlm.nih.gov/pubmed/33933440
http://dx.doi.org/10.1016/j.jlr.2021.100081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178125/
https://www.ncbi.nlm.nih.gov/pubmed/33933440
http://dx.doi.org/10.1016/j.jlr.2021.100081

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