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Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections

Functional circuits consist of neurons with diverse axonal projections and gene expression. Understanding the molecular signature of projections requires high-throughput interrogation of both gene expression and projections to multiple targets in the same cells at cellular resolution, which is diffi...

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Detalles Bibliográficos
Autores principales: Sun, Yu-Chi, Chen, Xiaoyin, Fischer, Stephan, Lu, Shaina, Gillis, Jesse, Zador, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178227/
https://www.ncbi.nlm.nih.gov/pubmed/33972801
http://dx.doi.org/10.1038/s41593-021-00842-4