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Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections
Functional circuits consist of neurons with diverse axonal projections and gene expression. Understanding the molecular signature of projections requires high-throughput interrogation of both gene expression and projections to multiple targets in the same cells at cellular resolution, which is diffi...
Autores principales: | Sun, Yu-Chi, Chen, Xiaoyin, Fischer, Stephan, Lu, Shaina, Gillis, Jesse, Zador, Anthony M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178227/ https://www.ncbi.nlm.nih.gov/pubmed/33972801 http://dx.doi.org/10.1038/s41593-021-00842-4 |
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