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LncRNA lnc‐ISG20 promotes renal fibrosis in diabetic nephropathy by inducing AKT phosphorylation through miR‐486‐5p/NFAT5

Long non‐coding RNA (lncRNA) lnc‐ISG20 has been found aberrantly up‐regulated in the glomerular in the patients with diabetic nephropathy (DN). We aimed to elucidate the function and regulatory mechanism of lncRNA lnc‐ISG20 on DN‐induced renal fibrosis. Expression patterns of lnc‐ISG20 in kidney tis...

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Detalles Bibliográficos
Autores principales: Duan, Yu‐Rui, Chen, Bao‐Ping, Chen, Fang, Yang, Su‐Xia, Zhu, Chao‐Yang, Ma, Ya‐Li, Li, Yang, Shi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178263/
https://www.ncbi.nlm.nih.gov/pubmed/33939247
http://dx.doi.org/10.1111/jcmm.16280