Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia

Drug‐mediated or medical condition‐mediated disruption of hERG function accounts for the main cause of acquired long‐QT syndrome (acLQTs), which predisposes affected individuals to ventricular arrhythmias (VA) and sudden death. Many Chinese herbal medicines, especially alkaloids, have risks of arrhy...

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Detalles Bibliográficos
Autores principales: Zhan, Ge, Wang, Fang, Ding, Yun‐qi, Li, Xiang‐hua, Li, Yue‐xin, Zhao, Zheng‐rong, Li, Jia‐xin, Liu, Yan, Zhao, Xin, Yan, Cai‐chuan, Li, Bao‐xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178274/
https://www.ncbi.nlm.nih.gov/pubmed/33939251
http://dx.doi.org/10.1111/jcmm.16292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178274/
https://www.ncbi.nlm.nih.gov/pubmed/33939251
http://dx.doi.org/10.1111/jcmm.16292

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