Therapeutic effect of SP‐8356 on pulmonary embolism‐associated cardiac injury is mediated by its ability to suppress apoptosis and inflammation

The cyclophilin A–CD147 interaction has been reported to be one of the most potential therapeutic targets for the treatment of acute pulmonary embolism. The signalling of extracellular signal‐regulated kinase 1/2 (ERK1/2) was also reported in the pathogenesis of cardiac injury. Since SP‐8356 is rega...

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Detalles Bibliográficos
Autores principales: Zhou, Jia, Liu, Kai, Feng, Cheng, Peng, Zhengliang, Luo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178275/
https://www.ncbi.nlm.nih.gov/pubmed/33942476
http://dx.doi.org/10.1111/jcmm.16535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178275/
https://www.ncbi.nlm.nih.gov/pubmed/33942476
http://dx.doi.org/10.1111/jcmm.16535

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