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Potent germline-like monoclonal antibodies: rapid identification of promising candidates for antibody-based antiviral therapy
In recent years, fully human monoclonal antibodies (mAbs) are making up an increasing share of the pharmaceutical market. However, to improve affinity and efficacy of antibodies, many somatic hypermutations could be introduced during affinity maturation, which cause several issues including safety a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178282/ https://www.ncbi.nlm.nih.gov/pubmed/34104872 http://dx.doi.org/10.1093/abt/tbab008 |