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Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress

Lipotoxicity has been shown to cause dysfunction of many organs and tissues. However, it is unclear whether lipotoxicity is harmful to the somatotrophs, a kind of cell that synthesize growth hormone (GH) in the pituitary. In this study, we performed an epidemiological study, serum levels of triglyce...

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Detalles Bibliográficos
Autores principales: Gong, Ying, Yang, Jianmei, Wei, Shuoshuo, Yang, Rui, Gao, Ling, Shao, Shanshan, Zhao, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178284/
https://www.ncbi.nlm.nih.gov/pubmed/33943005
http://dx.doi.org/10.1111/jcmm.16532