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The N(6)-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6
N(6)-methyladenosine (m(6)A) modification is widespread in messenger RNAs and increasing evidence suggests the crucial roles of m(6)A in cell differentiation and tissue development. However, whether m(6)A modulates the osteogenic differentiation of mesenchymal stem cells (MSCs) has not been fully el...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178363/ https://www.ncbi.nlm.nih.gov/pubmed/34088896 http://dx.doi.org/10.1038/s41419-021-03869-4 |