The monoamine stabilizer OSU6162 has anxiolytic-like properties and reduces voluntary alcohol intake in a genetic rat model of depression

Alcohol use disorders (AUD) often co-occur with anxiety and depressive disorders, and anxiety often drives relapse during alcohol abstinence. Optimal AUD pharmacotherapies may thus need to target both excessive alcohol intake and elevated anxiety. (−)-OSU6162 (OSU) is a monoamine stabilizer that att...

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Detalles Bibliográficos
Autores principales: Melas, Philippe A., Wirf, Malin, André, Helder, Jayaram-Lindström, Nitya, Mathé, Aleksander A., Steensland, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178366/
https://www.ncbi.nlm.nih.gov/pubmed/34088937
http://dx.doi.org/10.1038/s41598-021-91215-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178366/
https://www.ncbi.nlm.nih.gov/pubmed/34088937
http://dx.doi.org/10.1038/s41598-021-91215-1

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