ALS-linked FUS mutants affect the localization of U7 snRNP and replication-dependent histone gene expression in human cells

Genes encoding replication-dependent histones lack introns, and the mRNAs produced are a unique class of RNA polymerase II transcripts in eukaryotic cells that do not end in a polyadenylated tail. Mature mRNAs are thus formed by a single endonucleolytic cleavage that releases the pre-mRNA from the D...

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Detalles Bibliográficos
Autores principales: Gadgil, Ankur, Walczak, Agnieszka, Stępień, Agata, Mechtersheimer, Jonas, Nishimura, Agnes Lumi, Shaw, Christopher E., Ruepp, Marc-David, Raczyńska, Katarzyna Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178370/
https://www.ncbi.nlm.nih.gov/pubmed/34088960
http://dx.doi.org/10.1038/s41598-021-91453-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178370/
https://www.ncbi.nlm.nih.gov/pubmed/34088960
http://dx.doi.org/10.1038/s41598-021-91453-3

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