A critical role for Th17 cell-derived TGF-β1 in regulating the stability and pathogenicity of autoimmune Th17 cells

Pathogenic conversion of Th17 cells into multifunctional helper T cells or Th1 cells contributes to the pathogenesis of autoimmune diseases; however, the mechanism regulating the plasticity of Th17 cells remains unclear. Here, we found that Th17 cells expressed latent TGF-β1 in a manner dependent on...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Garam, Park, Young-Jun, Cho, Minkyoung, Moon, Heesu, Kim, Daehong, Kang, Chang-Yuil, Chung, Yeonseok, Kim, Byung-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178381/
https://www.ncbi.nlm.nih.gov/pubmed/34050263
http://dx.doi.org/10.1038/s12276-021-00632-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178381/
https://www.ncbi.nlm.nih.gov/pubmed/34050263
http://dx.doi.org/10.1038/s12276-021-00632-9

Ejemplares similares