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Synergistic cycles of protease activity and inflammation via PPARγ degradation in chronic obstructive pulmonary disease

Inflammation, oxidative stress, and protease–antiprotease imbalance have been suggested to be a pathogenic triad in chronic obstructive pulmonary disease (COPD). However, it is not clear how proteases interact with components of inflammatory pathways. Therefore, this study aimed to evaluate the effe...

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Detalles Bibliográficos
Autores principales: Kwak, Nakwon, Lee, Kyoung-Hee, Woo, Jisu, Kim, Jiyeon, Lee, Chang-Hoon, Yoo, Chul-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178386/
https://www.ncbi.nlm.nih.gov/pubmed/34021254
http://dx.doi.org/10.1038/s12276-021-00626-7