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PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis

Osteoporosis (OP) is the most common systematic bone disorder among elderly individuals worldwide. Long noncoding RNAs (lncRNAs) are involved in biological processes in various human diseases. It has been previously revealed that PAX8 antisense RNA 1 (PAX8-AS1) is upregulated in OP. However, its mol...

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Detalles Bibliográficos
Autores principales: Huang, Caiqiang, Li, Runguang, Yang, Changsheng, Ding, Rui, Li, Qingchu, Xie, Denghui, Zhang, Rongkai, Qiu, Yiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178389/
https://www.ncbi.nlm.nih.gov/pubmed/34012023
http://dx.doi.org/10.1038/s12276-021-00621-y