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AAV8 transduction capacity is reduced by prior exposure to endosome-like pH conditions

Adeno-associated virus (AAV) is an essential instrument in the neuroscientist’s toolkit, which allows delivery of DNA to provide labeling with fluorescent proteins or genetic instructions to regulate gene expression. In the field of neural regeneration, the transduction of neurons enables the observ...

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Detalles Bibliográficos
Autores principales: Lowell, Jeffrey A., Mah, Kar Men, Bixby, John L., Lemmon, Vance P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178773/
https://www.ncbi.nlm.nih.gov/pubmed/33229719
http://dx.doi.org/10.4103/1673-5374.299272