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Exploring conformational preferences of proteins: ionic liquid effects on the energy landscape of avidin

In this work we experimentally investigate solvent and temperature induced conformational transitions of proteins and examine the role of ion–protein interactions in determining the conformational preferences of avidin, a homotetrameric glycoprotein, in choline-based ionic liquid (IL) solutions. Avi...

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Detalles Bibliográficos
Autores principales: Shmool, Talia A., Martin, Laura K., Clarke, Coby J., Bui-Le, Liem, Polizzi, Karen M., Hallett, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178808/
https://www.ncbi.nlm.nih.gov/pubmed/34163590
http://dx.doi.org/10.1039/d0sc04991c