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Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms

BACKGROUND: Long-read sequencing is revolutionizing genome assembly: as PacBio and Nanopore technologies become more accessible in technicity and in cost, long-read assemblers flourish and are starting to deliver chromosome-level assemblies. However, these long reads are usually error-prone, making...

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Detalles Bibliográficos
Autores principales: Guiglielmoni, Nadège, Houtain, Antoine, Derzelle, Alessandro, Van Doninck, Karine, Flot, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178825/
https://www.ncbi.nlm.nih.gov/pubmed/34090340
http://dx.doi.org/10.1186/s12859-021-04118-3